The picture shows the results. On the left panel the white bands clearly indicate MMP activity in chronic wound fluid.
The
panel in the middle shows drastically reduced MMP activity when
TenderWet superabsorbent particles were present but physically
separated from the wound fluid proteins (containing MMPs).
Ant
the right panel shows that MMP activity is completely bocked with
the most potent inhibitor for MMPs (EDTA which is toxic to cells).
Please note that in all tree panels the same amount of chronic wound fluid was analyzed. These results suggest that MMPs can be present but they do not function properly anymore. Most importantly, this inhibition works over large distances.
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Click on image to enlarge
Matrix metalloportease inhibition in wound fluid over long distances
In each of the three panels the identical amouts
of the same chronic wound fluid were analyzed. MMP activity is strongly
reduced by TenderWet superabsorbent particles when direct physical
contact was excluded.
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