Systemic disease associated with impaired wound healing
The list below is not complete. Some of the diseases listed are very rare or limited to certain geographic regions such as the tropics or predominantly found in black Africans or black Americans.
Vascular diseases
 - chronic venous insufficiency
- peripheral arterial vascular disease
- primary/secondary lymphedema
Hematologic disease
 - polycythemia vera
- sickle cell anemia
- coagulation disorders
Chronic inflammatory disease
- vasculitis (any form)
- perforating dermatoses
- granuloma annulare
- necrobiosis lipoidica diabetorum
Metabolic disease
- diabetes mellitus
- gout
Tumors
- primary cutaneous tumors
- ulcerating metastases
Various diseases
- pyoderma gangraenosum
- X-ray treatment
- perniones
- burns
Infectious
- bacterial, fungal and
   parasite associated wounds

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