Inflammation
begins minutes after injury. The coagulation cascade is activated to
stop bleeding. When the clot is formed small protein fragments are
produced which attract inflammatory cells.
Platelets are trapped in the clot and release growth factors at the site of injury.
So, within minutes the basis for subsequent inflammatory changes is
laid and activation of the dormant cells at the wound edges can occur.
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Click on image to enlarge
Platelets in wound healing
Platelets become activated in the clot and release huge amounts of
growth factors and attract other, inflammatory cells.
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