On
a cellular and molecular level we know much less about impaired wound
healing than for normal tissue repair. After the initial trauma wound
healing may progress normally to any phase we have reviewed before.
Wounds may become stuck in any phase and cannot reach the next phase in
due time. A wound starts to become chronic.
Clinically
delayed healing wounds are very well described. Unfortunately, new
concepts how to treat these wounds have not been formulated. Despite
significant advances in basic research, patients only minimally
profited.
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